Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c72d118f5664072de841f9c5c34b9d99 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5005 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 |
filingDate |
2014-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e94c262239c1b25ebbd1dcd225f18410 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56d35f57715bcaaafd6e6d09bb044d17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88cb88034b0d81de55ec6fcf0417d5f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fdcaa3edc37230517cb5bf77cdda6eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_418bdf347633c3f8e9d2793d740782e7 |
publicationDate |
2016-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2016069782-A1 |
titleOfInvention |
Methods of analyzing an h&e stained biological sample |
abstract |
Methods comprising probing multiple targets in an H&E stained biological sample are provided. The methods include the steps of providing a hematoxylin and eosin stained biological sample containing multiple targets, optionally detecting H&E staining of the sample, removing the hematoxylin and eosin signals, and detecting additional features or targets in the biological sample. The detecting step may include performing the steps of binding at least one probe to one or more targets to the sample, detecting a signal from the probe and contacting the sample with a bleaching agent. The process of binding, detecting and bleaching may be iteratively repeated. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021281806-A1 |
priorityDate |
2013-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |