| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e40ceab05afbe887909abf7467edd987
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3fcb093a174d5182b5854b704cb09354 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0077
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0073
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A24B15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01H6-823
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6895
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A24B13-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01H5-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8243 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01H5-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A24B15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A24B13-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 |
| filingDate |
2015-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d5e8c880f791df8adad8557010263fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e630c0286478283ff991ed0bf3ef9ca0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfc3931af48d5cd1d976f341b03d3ff5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_677f4d027975206be468460820a262b0 |
| publicationDate |
2016-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2016057967-A1 |
| titleOfInvention |
Alteration of tobacco alkaloid content through modification of specific cytochrome p450 genes |
| abstract |
Compositions and methods for reducing the level of nornicotine and N′-nitrosonornicotine (NNN) in Nicotiana plants and plant parts thereof are provided. The compositions comprise isolated polynucleotides and polypeptides for cytochrome P450s that are involved in the metabolic conversion of nicotine to nornicotine in these plants. Expression cassettes, vectors, plants, and plant parts thereof comprising inhibitory sequences that target expression or function of the disclosed cytochrome P450 polypeptides are also provided. Methods for the use of these novel sequences to inhibit expression or function of cytochrome P450 polypeptides involved in this metabolic conversion are also provided. The methods find use in the production of tobacco products that have reduced levels of nornicotine and its carcinogenic metabolite, NNN, and thus reduced carcinogenic potential for individuals consuming these tobacco products or exposed to secondary smoke derived from these products. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019113360-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11773401-B2 |
| priorityDate |
2005-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |