Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f620648c8e70cc899f688e7918075741 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-346 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2015-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66a7e9544095bd449a9f323beaec370c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb84699a897866fe95f4efb28e13a8e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c4d523bfeea102860eb78b289925cf7 |
publicationDate |
2016-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2016053254-A1 |
titleOfInvention |
Treatment of genetic disorders associated with dna repeat instability |
abstract |
The current invention provides for methods and medicaments that apply oligonucleotide molecules complementary only to a repetitive sequence in a human gene transcript, for the manufacture of a medicament for the diagnosis, treatment or prevention of a cis-element repeat instability associated genetic disorders in humans. The invention hence provides a method of treatment for cis-element repeat instability associated genetic disorders. The invention also pertains to modified oligonucleotides which can be applied in method of the invention to prevent the accumulation and/or translation of repeat expanded transcripts in cells. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11111494-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10246707-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10876114-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2017175113-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10533178-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11427820-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11078486-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10006027-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10179912-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018152523-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10934547-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10308934-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019017047-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10913946-B2 |
priorityDate |
2006-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |