| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9fb7bbc09927d64558e1e99a3b7c719b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-86 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-82 |
| filingDate |
2014-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8da301f77e49a08c7d08ba5d670e688c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2d9b7f29942bea223473b0d889744fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9480421e5d541008945460cf9dd074be
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a8e2429b91f7b1bd2ae59428839f9e2 |
| publicationDate |
2016-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2016046578-A1 |
| titleOfInvention |
Inhibitors of prmt5 and methods of their use |
| abstract |
In one aspect, the invention relates to PRMT5 inhibitors, including optionally substituted N-alkyl-9H-carbazole analogs, derivatives thereof, and related compounds; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders of uncontrolled cellular proliferation and benign hematologic diseases using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113186153-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020205660-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115304503-A |
| priorityDate |
2013-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |