| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18d92c46f60af8af24e262b67381d7eb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3233 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2015-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77440ad5eccf03797b2ade66883b7da6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efef13fb37afbb87a7acb0d1693a7179 |
| publicationDate |
2016-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2016017327-A1 |
| titleOfInvention |
Phosphorodiamidate morpholino oligomers (pmos) and their use in suppression of mutant huntingtin expression and attenuation of neurotoxicity |
| abstract |
The present invention provides antisense phosphorodiamidate morpholino oligomers which are useful for the suppression or inhibition of the HTT gene involved in Huntington's disease. The oligomers can selectively suppress mutant forms of the HTT protein while allowing the normal protein to be expressed in sufficient quantity to retain its function in the cell. Methods for treatment of Huntington's disease are also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9617547-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9605019-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10329318-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10428019-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10149905-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10280192-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10144933-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9695211-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10160969-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10307434-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9982257-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10322173-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10724035-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10167309-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10590413-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10479995-B2 |
| priorityDate |
2014-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |