Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_452edf09f236371e61e3fd22a06ded78 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06121 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-195 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-072 |
filingDate |
2014-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07736e4d75ecfa6ad5c78051704a39a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7fef473d246460f9f644d461b2f5cf6 |
publicationDate |
2016-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2016016994-A1 |
titleOfInvention |
Inhibition of tumor growth with aggregates of small molecules |
abstract |
Disclosed herein are fibrillar molecular aggregates, which are morphologically and phenotypically similar to oligomers of aberrant proteins. The molecular aggregates, formed by self-assembly of small hydrophobic molecules, prevent the growth of microtubules. This unprecedented mechanism of “self-assembly to interfere with self-organization” allows inhibition of the growth of cancer cells. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11191724-B2 |
priorityDate |
2013-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |