| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_779dc7b7b9eaf2843cbfb21d196c7447 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0812 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-08 |
| filingDate |
2014-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_363b0c20da76cca9545a9c49945aaf4e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0851a48d885bdc3603f0f95f1201d0b8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad65aa3c49583c3b4949e3032d2e6675
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56b8d14df0fe07d9da9a53aa1107b3e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_335b829acbb2ba78db6d53ff0d79c921 |
| publicationDate |
2016-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2016016925-A1 |
| titleOfInvention |
Substituted (R)-3-(4-methylcarbamoyl-3-fluorophenylamino)tetrahydrofuran-3-encarboxylic acid (variants) and ester thereof, method for preparation and use |
| abstract |
The present invention relates to novel chemical compounds of the general formula 1—intermediate products in synthesis of androgen receptor inhibitors which are of interest as anticancer medicaments. The subject of the invention is also a method for preparation of novel compounds of the general formula 1.1—androgen receptor inhibitors. n Substituted 3-(4-methylcarbamoyl-3-fluorophenylamino)tetrahydrofuran-3-encarboxylic acids, or their esters of the general formula 1, 1.1 and stereoisomers thereof, n n n n n n n n n n n n wherein: R 1 =C 1 -C 4 alkyl; R 2 =H, CH 2 OCH 2 CH 2 Si(CH 3 ) 3 ; n n n n n n n n n n n n n n n n wherein: R 1 =H, C 1 -C 4 alkyl; R 2 =H, CH 2 OCH 2 CH 2 Si(CH 3 ) 3 . |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10450278-B2 |
| priorityDate |
2013-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |