http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016003803-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_626adcf93f576ecdaf0da53ad5dfb398 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate | 2014-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba5195cf539c59be497687e3da66f7fd |
| publicationDate | 2016-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2016003803-A1 |
| titleOfInvention | A screening method, a kit, a method of treatment and a compound for use in a method of treatment |
| abstract | A method of screening for a candidate compound for the treatment of a condition involving dysregulation of metabolism in a mammal, said method comprising bringing a compound into contact with at least one population of cells, comprising cells that express mTOR and Akt and that are capable of activating mTORC2 and Akt; determining mTORC2 activity and Akt activity in cells brought into contact with the compound, and identifying the candidate compound based on the determined mTORC2 activity and Akt activity. A kit for use in such a method of. A compound for use in a method of treatment of a condition involving dysregulation of metabolism in a mammal, and a method of treatment of such a condition. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9891212-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9657348-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017153737-A1 |
| priorityDate | 2013-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 242.