Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ada68032e6c5599de33d868231aaa52d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75b765b53e6651e9863a3a35e4c1e164 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-285 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-28 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-428 |
filingDate |
2015-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59efbeca3cf46f00abf98c3b455ae883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_875dccaeadce9ebb5fb332b9bea7f0f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4bb4613bd2661cca6e57ea9a683f922 |
publicationDate |
2015-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2015377912-A1 |
titleOfInvention |
Method for Determining and Treating Amyotrophic Lateral Sclerosis |
abstract |
The present invention provides a method of determining and treating amyotrophic lateral sclerosis (ALS) in a subject, comprising the following steps: (1) measuring a concentration of an autoantibody against high mobility group box 1 protein (HMGB1) in a biological sample from the subject; and (2) administering an effective amount of ALS-treating drug to the subject whose measured concentration of the autoantibody against HMGB1 is higher than 0.874 μg/ml. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020214538-A1 |
priorityDate |
2011-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |