| abstract |
A compound of formula (I) n n n n n n n n n n wherein X is O, CāO or S;n Y is N or CH; R 2 and R 4 are each independently H, ā(CH 2 ) p COOH, ā(CH 2 ) p CON(R 5 ) 2 or ā(CH 2 ) p COOC 1-6 alkyl; or R 2 and R 4 together form a 6-membered phenyl ring fused to the five membered ring; each R 1 is independently selected from H, halo (e.g. fluoro or chloro), C 6-10 aryl, C 7-12 arylalkyl, C 2-12 alkenyl; OC 1-12 alkyl, OC 2-12 alkenyl or a C 1-12 alkyl group; each R 5 is H or C 1-6 alkyl; each p is 0 to 3; n is 1 to 4; or a salt, ester, solvate, N-oxide, or prodrug thereof, e.g. a salt thereof |