| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a96a75a7cb08b859f8f77abf2d5cdd3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d24f3c493587a80cb2abbf22b34dc7d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8478c5668565566a828fbb54b8ed9fd2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41d6bb0d57436f8b78adb1c47f98a73d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0864
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0874
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0487
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0829 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0018
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502738
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502761 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2014-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88e9f96a6184ce71aafd3d55ce7812dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9abb6099b92ae53fdd41d0a8445f6f66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95b679dbd00633539f6c89046f344bc2 |
| publicationDate |
2015-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2015355165-A1 |
| titleOfInvention |
Microfluidic grid-based design for high throughput assays |
| abstract |
Microfluidic chips have been developed to perform a range of high-throughput biochemical and cell-based assays over recent years. We have formulated an innovative design for a microfluidic chip that resembles a microtiter plate by placing the test chambers (each test chamber contains cells) and top-loading drug inlets (one per test chamber) in a grid according to the ANSI/SBS standards, yet offers the miniaturization and fluid handling advantages of microfluidics. This ensures that our chip design is compatible with fluid handling and imaging equipment already in use for drug screening. We have determined a range of topologies that allow placement of various elements of this microfluidic network within the grid alignment constraints. We also developed a resistance equalization methodology to reduce variability across assays run in different chambers of the microfluidic chip. Additionally, it offers orders of magnitude miniaturization over multiwell plates, and potentially more reliable fluid handling. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114618359-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109490535-A |
| priorityDate |
2013-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |