Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_55c7033e5692e9bf2cfa3a5da5a578bc |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2469-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70503 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56983 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 |
filingDate |
2013-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_800cb3408bbf9064f13b273dcfa0994a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ca9e5e783e29992a63949327f49bf97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cd30e5bfa8651d97923e33a478b9151 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_200e4552b1c5ee1220171a182159db40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1545db8fe5f6f903e094c707e5aef170 |
publicationDate |
2015-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2015330993-A1 |
titleOfInvention |
Diagnostic, prognostic, therapeutic and screening protocols |
abstract |
The specification describes an antibody capture process comprising (i) obtaining a biological sample comprising antibodies, (ii) contacting the biological sample with recombinant pIgR or a dIgA-binding variant, wherein the pIgR or variant binds dIgA and forms a pIgR-dIgA complex. The process may further comprise (iii) directly or indirectly assessing the level of the pIgR-dIgA complex or the level of a complex between pIgR-dIgA and an antigen of interest. There is also an antibody capture process for determining gut wall integrity in a test subject, wherein the level or ratio of SIgA to dIgA is compared to a corresponding level or ratio from a control subject. The specification provides kits embodying the process and recombinant pIgR when used for, or for use, in capturing or detecting dIgA and/or IgM. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021026000-A1 |
priorityDate |
2012-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |