http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015317458-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7552d20057e28e83002141e7a2c63002 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8243 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8216 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8254 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F19-701 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C10-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-82 |
| filingDate | 2013-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1741c95e3526c9171b395b75e958597c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb31b987050f970f3abaf1df8e5b9bf6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5220d4762049d6fec8ae97cb2e69428e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9e0aaca7216f91eefe4ec5e8a978cf9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f3dbba9619437c21f940316c9b920e6 |
| publicationDate | 2015-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2015317458-A1 |
| titleOfInvention | In silico prediction of enhanced nutrient content in plants by metabolic modelling |
| abstract | The present invention relates to a method for identifying at least one metabolic conversion step, the modulation of which increases the amount of a metabolite of interest in a plant cell, plant or plant part, said method comprising establishing a stoichiometric network model for the metabolism of the plant cell, plant or plant part including the synthesis pathway for the metabolite of interest, identifying at least one candidate metabolic conversion step by applying at least one algorithm of Growth-coupled Design, and validating the at least one candidate metabolic conversion step by a constraint-based modeling approach in the stoichiometric network model, wherein an increase in the metabolite of interest occurring in said constraint-based modeling approach is indicative for a metabolic conversion step, the modulation of which increases the amount of the metabolite of interest in the plant cell, plant or plant part. The present invention further relates to a method for generating a plant cell, plant or plant part which produces an increased amount of a metabolite of interest when compared to a control, said method comprising identifying a metabolic conversion step, the modulation of which increases a metabolite of interest in a plant cell, plant or plant part, by the method for identifying a metabolic conversion step and modulating the said metabolic conversion step such that the amount of the metabolite of interest is increased in vivo in a plant cell, plant or plant part. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114624354-A |
| priorityDate | 2012-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 896.