Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a6c59a278d351dcf8b98afe8e3a63dfd |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-59 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-56 |
filingDate |
2014-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_980666a1eec18c2596bd7ad4f1b7636a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80ae5250268359549c0a91634b63d10f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_015345bba4488cb46e23f54bebd67f39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f044a93168a8699d619795532fcc48f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb5501219a92e4622860d82191cc6b31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7111d538a07d835d9ecbf36cc50d871f |
publicationDate |
2015-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2015315147-A1 |
titleOfInvention |
Compositions for modulating a kinase cascade and methods of use thereof |
abstract |
The invention relates to compositions comprising 2-(5-(4-(2-morpholinoethoxyl)phenyl)pyridin-2-yl)-N-benzylacetamide and its mesylate and dihydrochloride salts. The invention provides an efficient process for the synthesis of 2-(5-(4-(2-morpholinoethoxyl)phenyl)pyridin-2-yl)-N-benzylacetamide and its mesylate and dihydrochloride salts and methods for modulating one or more components of a kinase cascade using the compositions of the invention. The present invention also provides a novel polymorph of the mesylate salt of 2-(5-(4-(2-morpholinoethoxyl)phenyl)pyridin-2-yl)-N-benzylacetamide (Form A), characterized by a unique X-ray diffraction pattern and Differential Scanning Calorimetry profile, as well as a unique crystalline structure. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10106505-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10196357-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9926273-B2 |
priorityDate |
2006-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |