Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_faf522b8b83eded745c73018576219ba |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6875 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate |
2013-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_923a428ef4344536dc89a985447b3af7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0c8fe7af0f3665a386d24ee9a7e11da http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d938d31ab0deada359d183c9dcb8a3e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50179eaa1d30ce28f71848a435b5ab0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b385176acb006025305898f5ec4c409 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15a3e46fbfe9ef70ba4b41cfda9d55c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3933475908d97c55ea5a58bc464959d2 |
publicationDate |
2015-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2015299277-A1 |
titleOfInvention |
Agent for treating or preventing systemic inflammatory response syndrome |
abstract |
The present invention provides a therapeutic or prophylactic agent for systemic inflammatory response syndrome (SIRS), which contains a polypeptide comprising an amino acid sequence the same or substantially the same as the amino acid sequence of the N-terminal domain of pentraxin 3 capable of binding to histone to form a polypeptide aggregate, or a pharmacologically acceptable salt thereof. The present invention also provides a reagent for quantification and a quantification method of histone, which utilize the polypeptide or a pharmacologically acceptable salt thereof. Furthermore, the present invention provides a polypeptide aggregate containing the polypeptide or a pharmacologically acceptable salt thereof and histone and a production method thereof. |
priorityDate |
2012-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |