| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8c0982b0f02b1ed6d20a315370a3a3a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-18 |
| filingDate |
2013-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35c9805e92ecdf36aaf17c1e14e7821c |
| publicationDate |
2015-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2015291610-A1 |
| titleOfInvention |
C20' Urea Derivatives of Vinca Alkaloids |
| abstract |
A vinca alkaloid compound that is substituted at the 20′-position with a urea or thiourea group is disclosed. The urea's proximal nitrogen atom bonded to the 20′-position carbon atom is secondary, whereas the distal nitrogen atom can be unsubstituted only when the compound contains an optionally present 10′-fluoro substituent, and is otherwise preferably mono- or di-substituted. Methods of preparing the compounds are disclosed as are compositions for their use and methods of treatment using a compound. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10689381-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2018200774-B2 |
| priorityDate |
2012-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |