| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42a59c5faed1d0699d86edc5a2eee671 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2510-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-22056 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-22061
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6472
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6475
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-22062
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-22055
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-22059
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-22063
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-2206
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 |
| filingDate |
2015-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71dc17a1349e79d119c7ef848ce6160c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1e1fc6ef02ee7552fa22407d92a3ef1 |
| publicationDate |
2015-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2015284702-A1 |
| titleOfInvention |
Method for the determination of botulinum neurotoxin biological activity |
| abstract |
The present invention relates to means and methods for determining neurotoxin activity. Specifically, it relates to a polypeptide having caspase activity comprising a large subunit and a small subunit wherein the caspase further comprises a neurotoxin cleavage site which upon cleavage activates the caspase activity. Also encompassed are polynucleotides encoding the polypeptides as well as vectors or host cells comprising the polynucleotides. The present invention further relates to a method for determining neurotoxin activity in a sample based on the polypeptide of the invention as well as the use of the polypeptide for determining neurotoxin activity in a sample, in general. |
| priorityDate |
2011-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |