| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82a308524dd92f08d281d392c66fe6f7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2013-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f51a0b01fe92698ba7cdfac344c6275 |
| publicationDate |
2015-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2015275299-A1 |
| titleOfInvention |
miRNAs as Novel Therapeutic Targets and Diagnostic Biomarkers for Parkinsons Disease |
| abstract |
The disclosure provides pharmaceutical compositions including an oligonucleotide that down-regulates the over-expression of at least one miRNA of SEQ ID NOs: 1-283. The oligonucleotide may be complementary to the nucleotide sequence of at least one of SEQ ID NOs: 1-283, or hybridizes under stringent conditions to a nucleotide sequence of at least one of SEQ ID NOs: 1 -283. Further provided are methods of diagnosing Parkinson's Disease (PD) in a subject. The methods may include detecting the level of expression of at least one miRNA of SEQ ID NOs: 1-283 in a biological sample from the subject, and comparing the level of expression in the sample to the level of expression in a reference. Further provided are methods for treating, preventing, or reducing the risk of PD. Kits are also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11499184-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114107478-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102014390-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108531571-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11447772-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020227777-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9682095-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IT-202100012572-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022243836-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110279707-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190009722-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102062787-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102063244-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9441222-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110200986-A |
| priorityDate |
2012-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |