http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015272912-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c8e420dda7daeb30f131da50e2567001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cefe3c9c0c33bb3630d53be30553d180 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 |
filingDate | 2013-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a216cce50cebdfba2c8dbbcb3c6e56ba |
publicationDate | 2015-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2015272912-A1 |
titleOfInvention | Treatment or prevention of cardiovascular events via the administration of a colchicine derivative |
abstract | A method for the treatment or prevention of a cardiovascular event in a subject with atherosclerotic vascular disease comprising the step of:n b) administering a therapeutically effective amount of a compound of formula (I), a known colchicine derivative and/or a salt thereof nn n n n n n n n n n wherein: n R 1 , R 2 , R 3 , R 4 , R 9 , R 10 , R 11 and R 12 independently represent hydrogen, C 1-4 alkyl, C 2-4 alkenyl, C 3-6 cycloalkyl, halogen, C 1-4 haloalkyl, nitro, amino, C 2-4 acylamino, C 1-4 alkyl or dialkylamino, hydroxyl, C 1-4 alkoxy, C 1-4 alkylthio, a group of the formula —SO 2 N(R x ) 2 or SO 2 R x where R x is C 1-4 alkyl, C 1-4 acyloxy, or optionally substituted phenyl, optionally substituted phenoxy; n R 7 and R 8 independently represent hydrogen, C 1-4 alkyl or C 1-4 acyl; and n R 5 ′, R 5 ″, R 6 ′ and R 6 ″ independently represent hydrogen, C 1-4 alkyl, C 2-4 alkenyl, C 3-6 cycloalkyl, halogen, C 1-4 haloalkyl, nitro, amino, C 2-4 acylamino, hydroxyl, C 1-4 alkoxy or C 1-4 alkylthio a group of the formula —SO 2 N(R x ) 2 or SO 2 R x where R x is C 1-4 alkyl, n C 1-4 acyloxy, or optionally substituted phenyl. |
priorityDate | 2012-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 180.