Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0249c8c96ed09a989cb0d43c51a3060d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y203-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1029 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-06 |
filingDate |
2015-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da21bacb4bef1f0bfcd1999a61498740 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b0fbbc39c999c3d509d05584fbe3881 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_310ee18a1ef0abf136c0b2c6563dda90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f506df58539aad088b72a8ffe9cfc1fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c806e8ddffe266c35693ce87c6146fb |
publicationDate |
2015-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2015259718-A1 |
titleOfInvention |
Lov-d acyltransferase mediated acylation |
abstract |
Methods for the improved acylation of chemical substrates using LovD acyltransferases, thioesters having acyl groups, and (i) thiol scavengers and/or (ii) precipitating agents are presented. An improved method for the production of simvastatin using (i) activated charcoal as a thiol scavenger and/or (ii) ammonium hydroxide as a precipitating agent is also presented. |
priorityDate |
2009-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |