Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06490d34c45ae74ae0d818a0ad5a7667 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e8a1ca26af8abc83e59eb6712107645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_add2e00afce8951965b94b0376b6040c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c72f098a0cd65c9931ae17309bd7a5a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B25-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-436 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C20-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C20-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F19-706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06F19-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7064 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-436 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7064 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-00 |
filingDate |
2014-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50fedeb74c7fd77477736b88b95b6209 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3b3e4d1cbff5023eae40585348ea4de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e14e9d26f3ad32918d2c0355e075e9b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5575b111d33859a9d30547f9b3738202 |
publicationDate |
2015-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2015254433-A1 |
titleOfInvention |
Methods and Models for Determining Likelihood of Cancer Drug Treatment Success Utilizing Predictor Biomarkers, and Methods of Diagnosing and Treating Cancer Using the Biomarkers |
abstract |
A method of identifying one or more biomarkers associated with one or more drugs effective to stop or repress proliferation of cancer cells, and a system for predicting effectiveness of the same. The method includes statistically analyzing (i) a first dataset of expression levels of proteins or glycoproteins in the cancer cells and (ii) a second dataset of responses of the cancer cells to drugs to identify at least one biomarker associated with effective repression of the cancer cells, and correlating or associating at least one protein or glycoprotein biomarker with a response of the cells to at least one of the drugs effective to stop or repress the proliferation of the cancer cells. The protein and/or glycoprotein expression level datasets may be generated experimentally or taken from published information. The method advantageously determines and/or predicts drug sensitivity of various cancer cells using protein and glycoprotein biomarkers. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105859872-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11705220-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110672848-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111052247-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10665442-B2 |
priorityDate |
2014-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |