abstract |
This invention provides processes for preparation of 3-alkyl indoles of Formula 1: wherein A 1 , A 2 and A 3 are independently selected from the group consisting of: H, X, OR 1 , CN, CONR 2 2 and C0 2 R 3 ; R 1 is C 1 -C 6 alkyl; R 2 is H or C 1 -C 6 alkyl; R 3 is C 1 -C 6 alkyl; LG is a leaving group; X is a halogen; and n is 1, 2 or 3. |