abstract |
The present invention relates to alpha hydroxy amides including compounds of formula I n n n n n n n n n n and related compounds and their use in the prophylaxis and treatment of inflammatory disorders and diseases, wherein:n T 1 denotes one of the following groups: nn n n n n n n n n n n n T 2 -W denotes one of the following groups: n n n n n n n n n n n n n n n n W denotes a single bond, or a group selected from —CHR c — and —CH═CH—; and n R W denotes a group selected from H, Hal, linear or branched alkyl, Ar, Het, Cyc, —(CH 2 ) n Ar, —(CH 2 ) n Het, —(CH 2 ) n Cyc, —(CH 2 ) n OAr, —(CH 2 ) n OHet, —(CH 2 ) n OCyc, or A. |