| abstract |
The present invention provides a compound of formula A: n n n n n n n n n n or a pharmaceutically acceptable salt thereof, wherein B, Q, R 1 , R 5 , R 6 , R 7 , R 8 and Z are as defined herein, which is a 2′-branched nucleoside useful for the treatment or prevention of viral infections, particularly dengue fever, yellow fever, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, Kunjin virus, Murray Valley encephalitis, St Louis encephalitis, Omsk hemorrhagic fever virus, bovine viral diarrhea virus, Zika virus and Hepatitis C virus. |