abstract |
This invention provides for prodrug Compounds I, pharmaceutical compositions thereof, and their use in treating HIV infection. n n n n n n n n n n wherein:n nX is C or N with the proviso that when X is N, R 1 does not exist;n nW is C or N with the proviso that when W is N, R 2 does not exist;n nV is C;n nE is hydrogen or a pharmaceutically acceptable salt thereof; andn nY is selected from the group consisting ofn n n n n n n n n n n Also, this invention provides for intermediate Compounds II useful in making prodrug Compounds I. n n n n n n n n n n wherein:n nL and M are independently selected from the group consisting of C 1 -C 6 alkyl, phenyl, benzyl, trialkylsilyl, -2,2,2-trichloroethoxy and 2-trimethylsilylethoxy. |