Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8ebd1f43e0c8abedaf438d64d2a27be http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe5c71a8271138b2ae5558d57036c01f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9a0311f80d80eaf1a14993e696ebe246 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79b4e51ee2130481fc3aab197ebe70c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42d1d28b2a0dc25797ac5adb14ba929e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2012-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f40b1c0a2b60ade4bdaa0ff81b7a993e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc3bbac4a5df45e62f05f6f9b3571c45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ffe311639b0934fc143995f64896200 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce05d8569ec72c465291e9363c9ba5e2 |
publicationDate |
2015-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2015225796-A1 |
titleOfInvention |
Methylation analysis on self-samples as triage tool for hpv-positive women |
abstract |
The inventors now have developed a (molecular) diagnostic assay based on detection of alterations in markers MAL and hsa-mi R124, in particular promoter hypermethylation, to identify human papillomavirus (HPV)-induced high-grade precancerous lesions such as premalignant cervical lesions of invasive cervical cancer, within cell material obtained via self-sampling. In particular, the present invention relates to the use of the MAL gene (including its promoter) and the hsa-mi R124 gene as marker for HPV-induced high-grade premalignant lesions, allowing early detection and a better treatment option for the individual patient. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11441181-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11649210-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11649211-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021172029-A1 |
priorityDate |
2011-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |