| abstract |
The invention provides a 1,3,5-substituted indole wherein the substituent at position 1 is a C6 to C12 alkyl group; the substituent at position 3 is CH 2 NR 1 R 2 wherein R 1 is H or C1 to C3 alkyl, R 1 being optionally substituted with —OH, —SH, —NH 2 or NHalkyl, wherein alkyl is a C1 to C4 alkyl group, and R 2 is C1 to C3 alkyl or (CH 2 ) n bonded to position 2 of the indole, wherein n is 1, 2 or 3; and the substituent at position 5 is either an optionally substituted nitrogen containing heteroaromatic ring or an aminosulfonylphenyl group or an alkylsulfonylphenyl group. |