| abstract |
The present disclosure provides NO-releasing guanidine-chromene conjugates, having the structure of Formula (I): n n n n n n n n n n wherein R 1 , R 2 , R 3 , R 4 , R 10 , and L are as defined in the detailed description; pharmaceutical compositions comprising at least one of the compounds of Formula (I); and methods useful for healing wounds, preventing and treating cancer, or treating actinic keratosis, cystic fibrosis, acne, or a disease mediated by arginine deficiency using a compound of Formula (I). |