abstract |
A vaccine based on the chimeric protein consisting of immunogenic epitopes of conservative Streptococcus pneumoniae proteins: PspA, Spr1895, and PsaA, as well as flagellin components (FliC1, FliC2) functioning as safe adjuvant, the proteins or the peptides homologs to those to not less than 60% of their amino acid sequence, connected via flexible links. |