| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ca353589c8f95210cff7a59c1902c57 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6439
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-0846
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-086 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6458
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5032
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N15-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2014-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b7be9489d0f58f6e84e592168a7fd37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da970a6c0c7ace908cf5fe23bc0f1331
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3ff7343822aff58bc04d4480bf06818
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c239f8b64f7f27be8d99f55e839cc712
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3dbefb3581f358847fe6b1fc8f72729 |
| publicationDate |
2015-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2015153326-A1 |
| titleOfInvention |
Quantitative analysis of contact-dependent cell-to-cell transfer and disease transmission |
| abstract |
A method for a microscope-based quantitative analysis of contact-dependent cell-to-cell transfer between cells. Single donor cells containing a traceable marker are cultured in a lawn of acceptor cells to allow cell-to-cell transfers. The donor and acceptor cells are then imaged and/or stained for microscopy to determine the location, shape and volumes of donor cells and of surrounding acceptor cells within selected regions of interest. The spatial distribution of the traceable marker in each volumetric picture element of the region of interest is determined and analyzed to determine quantitatively and qualitatively the substance transfer. The method allows a reliable quantitative evaluation of the effect of an active agent on cell-to-cell molecular communication and disease transmission. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020243615-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11066650-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108956416-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11767515-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11584916-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3976767-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11053477-B2 |
| priorityDate |
2013-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |