http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015133388-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ee602c630e57f59c6cfc1c1634e36064 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1703 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
filingDate | 2015-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_947783fcbc2b9b601e4448e265124a80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed628f899a590b88c60979de5b490af4 |
publicationDate | 2015-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2015133388-A1 |
titleOfInvention | Acetylated crystallin polypeptides and mimetics thereof as therapeutic agents |
abstract | A method of inhibiting, reducing, and/or treating pathological apoptosis and/or protein aggregation in a subject includes administering to the subject an amount of a therapeutic polypeptide effective to inhibit, reduce, and/or treat the pathological apoptosis and/or protein aggregation. The therapeutic polypeptide including at least one of acetylated αA-crystallin, acetylated αB-crystallin, acetylated fragments thereof having molecular chaperone activity, and/or polypeptide mimetics thereof that can inhibit pathological protein aggregation and/or pathological apoptosis. |
priorityDate | 2012-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 523.