abstract |
This invention relates to the isolation, and use of a plant extract in the treatment of skin hyper-pigmentation. More particularly, this invention relates to the isolation of a tyrosinase inhibitor in an extract of plant material from the Greyia radlkoferi ( G. radlkoferi ) plant, the extract including 5,7-dihidroxyflavone[(2S)-pinocembrin]; 2′, 6′-dihydroxy-4′-methoxydihydrochalcone; 2′,4′,6′-trihydroxyhydrochalcone; 3,5,7-trihydroxyflavone and 4′,5′7-thhydroxyisoflavone. |