Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7d007df0e92f4a5cb4c6420e2c4309c1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-40 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
filingDate |
2013-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18bbaade9cab38183c43f61c5ef70d99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afca33eafaa5d5ff278a4ec47b1ddc15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a760b0886627cbd4c4f0771a52aafbb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f6c0b908ef25d9a801dde2fb78a7954 |
publicationDate |
2015-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2015079682-A1 |
titleOfInvention |
Non-viral episomal suicide construct |
abstract |
The invention includes compositions and methods for the selective expression of a target gene in a subset of cells. In certain embodiments, the present invention includes a construct comprising a first nucleic acid sequence comprising an episomal maintenance element and a second nucleic acid sequence comprising a target gene wherein the expression of the episomal maintenance element is regulated by a constitutive promoter and the expression of the target gene is regulated by a non-constitutive promoter. The construct is able to maintain episomal state, no matter whether the target gene is expressed in the cell. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11723987-B2 |
priorityDate |
2012-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |