http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015057185-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-581 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-006 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-84 |
| filingDate | 2013-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ec062a2c9ddd36fc2aebe5c2303a3f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3e346ff0a223973907cb1b25c7891b1 |
| publicationDate | 2015-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2015057185-A1 |
| titleOfInvention | Reaction-based fluorescent probe for selective detection of carbon monoxide using metal-mediated carbonylation |
| abstract | Carbon monoxide (CO) is a member of the gasotransmitter family that includes NO and H 2 S and is implicated in a variety of pathological and physiological conditions. Whereas exogenous therapeutic additions of CO to tissues and whole animals have been well studied, the real-time spatial and temporal tracking of CO at the cellular level remains an open challenge. We now report a new type of turn-on fluorescent probe for selective CO detection by exploiting palladium-mediated carbonylation reactivity. The compounds of the invention are capable of detecting CO both in aqueous buffer and in live cells with high selectivity over a range of biologically relevant reactive small molecules, providing a potentially powerful approach for interrogating its chemistry in biological systems. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112500427-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105623647-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105885830-A |
| priorityDate | 2013-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 276.