http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015056699-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_57efe0098d4727fc5e1c243467e1d072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b1f34ab4afbe49ea6611dfd13bd7b5c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9061cf80042e84d5a40aea0d332b68d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2a0e759e7b4ef073bcd9d5f2c80fb73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_247fea24df669e1886277335d2934c5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7e500057e3c4c9ca79f9383b55f110a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fc9240cd2fa1c3e601606663b662756e |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D453-06 |
filingDate | 2012-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_491f07bf73920d40703e31f68a062b98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf3cb57f108ac85aeb60aef1658c85ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a86e7bdb382c4e0322848fa277074e86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4d58cb998625fe5b864c61640442cf3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb4ed30de2043150c448965fd3a425bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c0b246c85ab653f04aa204235d4fa58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47e4c6fb5c7fbd93c0e05f41b2b9ddb0 |
publicationDate | 2015-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2015056699-A1 |
titleOfInvention | Small molecule inducers of gdnf as potential new therapeutics for neuropsychiatric disorders |
abstract | This invention provides a compound having the structure n n n n n n n n n n n n wherein n A is a ring structure, with or without substitution; n Z is present or absent and when present is n n n n n n n n n n n n n n n n n n wherein n n is 0, 1, 2, 3, or 4; n Y is —(CR 11 R 12 )—, —NH(CR 11 R 12 )—, or —O(CR 11 R 12 )—,n wherein R 11 and R 12 are each hydrogen or combine to form a carbonyl; n n n n R 1 , R 2 , R 3 , R 4 , R 5 and R 6 are independently H, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted heteroaryl, hydroxyl, amino, ester or amide; n α represents a bond, which is present or absent and when α is present, then R 7 and R 8 are absent; n R 7 and R 8 are present when α is absent and are independently H, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted heteroaryl, hydroxyl, amino, ester, amide or R 5 and R 7 combine to form a carbonyl or R 6 and R 8 combine to form a carbonyl; n R 9 and R 10 are each hydrogen or combine to form a carbonyl; and n when α is present, Z is n n n n n n n n n n n n n n where n=1, Y is —(CR 11 R 12 )— where R 11 and R 12 are H, A is unsubstituted indole attached at the 3-position of the indole, R 3 , R 4 , R 5 , R 6 , R 9 and R 10 are each H, and one of R 1 or R 2 is H, then the other one of R 1 or R 2 is other than H or ethyl,n nor a pharmaceutically acceptable salt, diastereomer, or enantiomer thereof. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10961244-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10844027-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10183919-B2 |
priorityDate | 2011-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1384.