| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e41651508566f0385833e1ba14a21ffd |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2531-119
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2565-537 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6846
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6853
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6874
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6834
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-46 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 |
| filingDate |
2012-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6b32eae9ba6aff1ff128bc5598e3b5c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b27a099bb130289941d3ca90693033c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_309ecd90983baf36ab7c868efb98a677
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fd1d4931bb8928b8d29d0cd00c69fed |
| publicationDate |
2015-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2015031026-A1 |
| titleOfInvention |
Enhanced ligation reactions |
| abstract |
In some embodiments, methods for ligating nucleic acid ends comprise: conducting a nucleic acid ligation reaction in the presence of at least one agent that generates a ligatable terminal 5′ phosphate group by removing an adenylate group from a terminal 5′ phosphate of a nucleic acid. In some embodiments, an aprataxin enzyme can catalyze removal of an adenylate group from a terminal 5′ phosphate of a nucleic acid. In some embodiments, methods for ligating nucleic acid ends comprise: conducting a nucleic acid ligation reaction in the presence of an aprataxin enzyme under conditions suitable for ligating nucleic acid ends. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11124789-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10626390-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3848457-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017139260-A1 |
| priorityDate |
2010-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |