http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015011767-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9e6a0102f7dc0397aaeb636aa13eafb |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4748 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4748 |
| filingDate | 2014-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccd2b1860f37be7571e25f7f482a6cf8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_139fc614b43326c4dc187331bf007f15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0114830e5d85a717079a1f533825dfd6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b09decc1e880b6affd9082b7b960697 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c92d8efa2b534b09886fb8ed74c8c696 |
| publicationDate | 2015-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2015011767-A1 |
| titleOfInvention | Use of koumine and its homologues in preparation of medicament for treatment of autoimmune diseases of involved bones and joints |
| abstract | The present invention discloses an application of koumine and homologue thereof in preparation of drugs for treating autoimmune diseases involving bones and joints including rheumatoid arthritis, spondylitis ankylopoietica or the like, in particular an application of Gelsemium alkaloid monomer koumine and homologue thereof or pharmaceutically acceptable salt thereof as active ingredient in preparation of drugs for treating autoimmune diseases involving bones and joints including rheumatoid arthritis, spondylitis ankylopoietica or the like. The result of pharmacology experiment shows that koumine can decrease the generation of organism antibody against autoimmune diseases involving bones and joints in a dose dependent manner, improve symptoms of swelling and hyperalgesia, reduce arthritis index, reverse joint pathological changes, and has no serious shortage of commonly used clinical drugs; thus koumine has an effect against autoimmune diseases involving bones and joints including rheumatoid arthritis, ankylosing spondylitis etc. with strong potency and low toxicity. Koumine can be developed into a new drug for treating autoimmune disease involving bones and joints including rheumatoid arthritis, spondylitis ankylopoietica etc., which has a clear industrial prospect. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113025581-A |
| priorityDate | 2011-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.