| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aadfcecd6e0d29bc5e6d608d5fa55f4d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a56c9ce9fc84e1c38dcaac3380a18b85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_17e6c778a71c468773a533a0b4dcd1e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e563948c8ad4f38055f487466c69431 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1635
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1682
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-366
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-397
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-541 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-541
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-366
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-397 |
| filingDate |
2012-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20d9036430f3b114deea1972801189de
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1bab5478b8ef3f6725a07118e50b4ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9fed4d224de9e1c76cdea4a243101f5 |
| publicationDate |
2015-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2015011525-A1 |
| titleOfInvention |
Solid dispersion of poorly soluble compounds comprising crospovidone and at least one water-soluble polymer |
| abstract |
A stable ternary solid dispersion composition with enhanced physical stability and/or bioavailability comprising: (a) about 1% wt. to about 50% wt. of one or more poorly soluble active pharmaceutical ingredient (API) which belongs to Biopharmaceutics Classification System (BCS) class II and/or IV; (b) about 11% wt. to about 50% wt. of at least one water-soluble polymer; and (c) about 20% wt. to about 99% wt. of crosslinked polyvinylpyrrolidone (crospovidone, a water-insoluble polymer). The solid dispersion is capable of inhibiting crystallization of API in solid state and/or aqueous gastrointestinal tract (GIT) medium. Also disclosed is a method of preparation of such solid dispersion composition by fusion or solvent or fusion-solvent method. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11191761-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112842998-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111419788-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114302710-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114652685-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11179392-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023077447-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021041824-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112165958-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115192530-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111904935-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018510221-A |
| priorityDate |
2011-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |