| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7d241434dd2e686fcc5aab7061164f8c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e071d18fea054bf8d1420d483e78ed1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2570-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2458-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-055 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-465
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-4633
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N24-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-055
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5038 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2013-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3635158b29b142fb09bd1033f2f1445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce95fb40404f2e33b391cf35ebd86fee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a926d54895f2fc8c5bcfe96a8c862268 |
| publicationDate |
2015-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2015005243-A1 |
| titleOfInvention |
Nmr-based metabolite screening platform |
| abstract |
Methods that enable one to specifically measure the metabolic product of a particular molecule in relatively few cells, e.g. primary cells, are described. The methods involve optionally preloading cells with labeled substrate (e.g. labeled by 13 C, 15 N, or 31 P). The methods allow for easy identification of metabolites that are differentially generated in cells of different phenotypes. The new methods for unbiased multi-dimensional NMR screening and rapid and efficient analysis of the NMR screening identify differentially expressed metabolites in different cell or tissue types. Analysis of the differentially expressed metabolites can present unique druggable targets to which small molecule therapeutics can be designed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11561271-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11579225-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11366102-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016061922-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11237237-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10132900-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020081326-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020116657-A1 |
| priorityDate |
2012-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |