http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014377819-A1

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5eba7ca689215167b9f91fe96596a431
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filingDate 2011-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e39d55cd10a2d97222280d4585542419
publicationDate 2014-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2014377819-A1
titleOfInvention Process for producing microbial copolyesters from sucrose-containing feedstocks
abstract A process for producing hydroxyalkanoate copolymers, which comprises: (i) pre-treating a sucrose-containing feedstock in an acidic solution; (ii) feeding the pre-treated feedstock into a bioreactor containing polyhydroxyalkanoate producing microbial cells; (iii) cultivating the polyhydroxyalkanoate producing microbial cells to form a cell mass containing the hydroxyalkanoate copolymers; (iv) recoverying the hydroxyalkanoate copolymers from the cell mass. The pre-treating step has the main function of hydrolyzing sucrose into glucose and fructose, which in turn are converted into 4-ketovaleric acid to give a mixture of mono-saccharides and organic precursors for microbial synthesis of hydroxyalkanoate copolymers, and particularly of PHBVV ter-polymers. Complex and expensive purification processes of the substrates obtained from the pre-treating step are not needed. The solutions can be directly used as the feeding solutions for microbial PHA biosynthesis.
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