| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fcf3369b7b64a07ba16be10032c61b40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b6b9fb2b66fcec353a5cd7838d10b5a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_324f02bbaa9087f036e446bb1c3183a3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_958a34f18f647b045ad75f65758f160d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_67d4fa236687e935ef2e04e5f94d72c6 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 |
| filingDate |
2012-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c9b495a55a949c6f7b599c8e89e4334
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a12928a0d972947e7c74e2bfd06328c0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a16ffde70550d29b3958400f16be022a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0392261278c2cfa3f078ea5da5f87caf |
| publicationDate |
2014-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2014370528-A1 |
| titleOfInvention |
Proteasome Deubiquinating Inhibitor Screening |
| abstract |
A method for screening a compound to determine whether the compound is a proteasome deubiquinating inhibitor of high specificity comprises contacting the compound with human 19S regulatory particles (19S RP) of 26S proteasome and determining whether the compound inhibits activity of deubiquinating (DUB) enzymes UCHL5 and USP14; inhibition of UCHL5 and USCP14 activities indicates that the compound is a proteasome deubiquinating inhibitor of high specificity. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11092602-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017007858-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017066697-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10682362-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018140907-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110831595-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10947199-B2 |
| priorityDate |
2011-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |