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filingDate 2014-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2014-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2014364371-A1
titleOfInvention Direct drug delivery system based on thermally responsive biopolymers
abstract A method for delivering a drug depot of a compound of interest to a selected region in a subject. The method comprises administering a composition directly to said region of interest, the composition comprising the compound of interest to be delivered (such as an antiinflammatory agent or a chemotherapeutic agent) and a polymer (such as an elastin-like peptide or ELP) that undergoes an inverse temperature phase transition, so that a sustained release of the compound of interest at the selected region is provided. Compositions useful for carrying out the invention are also described.
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