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filingDate 2012-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67a06db7f289fa542d6d182979e42ed9
publicationDate 2014-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2014349277-A1
titleOfInvention Anti-human norovirus gii antibody
abstract Provided is an anti-human-norovirus GII antibody which responds to substantially all genotypes of the human noroviruses belonging to GII and which can comprehensively detect such human noroviruses GII. n The anti-human-norovirus GII antibody that binds to at least one of epitopes which are contained in amino acid regions represented by the following formulas (1) and (2): n P-X 1 -X 2 -P-G-Eā€ƒā€ƒ(1)n n X 3 -X 4 -X 5 -F-Y-X 6 -L-X 7 -P-X 8 ā€ƒā€ƒ(2)n n (wherein, X 1 represents L, V, N, T, S, M, or R; X 2 represents F, Y, or M; X 3 represents V or G; X 4 represents N or S; X 5 represents Q, P, or S; X 6 represents S, T, or I; X 7 represents A or S; and X 8 represents M or V), and of an epitope formed of amino acid 483 of the amino acid sequence represented by SEQ ID NO: 1, or an epitope formed of an amino acid corresponding to amino acid 483, the regions and the amino acids being present in the P domain of a capsid structural protein of a human norovirus GII.
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