Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a168d25859aa8740172cf743ecc328c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aaf65bc56a7e238e6e73910ddaf2ca4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8088991ee02d98918c657dc062eea8af http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_11fccec28b3f6315c93df756bf9b5c17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9f218ced6ba06e24bfaa38739487aa2d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6911 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
filingDate |
2012-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d71c38fe8deeb0e792f3f4a99b37d74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40be6e31658ecebee559249c30e3c6ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e3ea5efa193d134fa9768c367e90816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b29a6a502b6d21f8621c246708fd619c |
publicationDate |
2014-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2014335164-A1 |
titleOfInvention |
Liposomes and its production method |
abstract |
The present invention is the use of conjugated peptide sequences for inclusion in liposomal membranes. The combination can be done with folic acid or with an antibody of folic acid receptor coupled to N-terminal peptide. The presence of these peptides conjugated to liposomal formulations allows the targeting and subsequent release of therapeutic agents and/or imaging agents to cells expressing folic acid receptor. n The developed method combines the ability of liposomes in the transport and release of drugs and the specific expression of folic acid receptor on the surface of cell membranes that allow transmembrane transport mediated by specific liposomes. Thus allows the transport of therapeutic agents and/or imaging agents, which are inside the liposome, either hydrophobic or hydrophilic. The therapeutic agents can be either pharmacological compounds (active agents) or siRNAs (small interference RNA) specific to defined target genes. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020240445-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10653796-B2 |
priorityDate |
2011-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |