| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c2e4a4ba842344815faabe370e037465
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_70e9368bd42f99c6c391f6fdc7135cc4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ccc1eb063f0f0ca783b6e7c3c5d82dd6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8cef91f4e40692dea3d904bb9157ba3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c4f7278569f293ccadab3b288f741b2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a12a9aa7e03ed0fd4a26fa0c7ac20e76 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-2221
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-64 |
| filingDate |
2012-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d15081bc740dc4d6509971ef8c41bbc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adf3565e14901c24dc9aec3ed4e37b30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21ccfbbef14b3c9c27e830c6cd28ffdf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23fb7d9961329e05e567315ca4177a98
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0360ad89601f67e390fe653db1187a7c |
| publicationDate |
2014-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2014328900-A1 |
| titleOfInvention |
Process for preparing human relaxin-2 |
| abstract |
A process for preparing human relaxin-2 having the following amino acid sequence: n A chain: n n n n n n (SEQ ID NO: 1) n n pGlu-Leu-Tyr-Ser-Ala-Leu-Ala-Asn-Lys-Cys-Cys-His- n n n n Val-Gly-Cys-Thr-Lys-Arg-Ser-Leu-Ala-Arg-Phe-Cys n n n n n n n n n n n n B chain: n n n n n n (SEQ ID NO: 2) n n Asp-Ser-Trp-Met-Glu-Glu-Val-Ile-Lys-Leu-Cys-Gly- n n n n Arg-Glu-Leu-Val-Arg-Ala-Gln-Ile-Ala-Ile-Cys-Gly- n n n n Met-Ser-Thr-Trp-Ser; n n n n n n n n n n n n n n comprising the following steps: n providing the amino acids necessary for the synthesis of the A and B chains with usual protective groups, wherein the cysteines are employed as trityl-protected amino acids (L-Cys(Trt)-OH); n effecting a chromatographic purification of the individual chains A and B after the solid state synthesis; n followed by the simultaneous folding and combination of the individual chains A and B in ammonium hydrogencarbonate buffer at pH 7.9 to 8.4; and n subsequent purification of the relaxin-2 formed. |
| priorityDate |
2011-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |