| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e96ca33f6f787323d29cd7e8453d3e31 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-726
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54366
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70571
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-723 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
| filingDate |
2014-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee2813f50c616d0a6097a8ada1794c18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_641e042c1ccb186ec56b4a61ae14a71f |
| publicationDate |
2014-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2014316116-A1 |
| titleOfInvention |
Methods for screening for binding partners of g-protein coupled receptors |
| abstract |
A method of producing a conformational specific binding partner of a GPCR, the method comprising: a) providing a mutant GPCR of a parent GPCR, wherein the mutant GPCR has increased stability in a particular conformation relative to the parent GPCR; b) providing a test compound; c) determining whether the test compound binds to the mutant GPCR when residing in a particular conformation; and d) isolating a test compound that binds to the mutant GPCR when residing in the particular formation. Methods of producing GPCRs with increased stability relative to a parent GPCR are also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017027523-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10458993-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10766945-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11673938-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016067094-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3839061-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10126313-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4177899-A1 |
| priorityDate |
2007-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |