| abstract |
A problem is to provide a monolithic structure that is a porous body formed of a polysaccharide being a naturally-occurring polymer, and has continuous pores having an average pore diameter suitable for biomolecule separation to allow formation into an arbitrary shape, and a manufacturing method therefor. A solution is to manufacture the polysaccharide monolithic structure by a method including a first step for dissolving a polysaccharide into a mixed solvent including a solvent into which the polysaccharide is soluble and a solvent into which the polysaccharide is insoluble, at a temperature lower than a boiling point of the mixed solvent, to give a polysaccharide solution, and a second step for cooling the polysaccharide solution to give the polysaccharide monolithic structure. The polysaccharide monolithic structure obtained is a porous body having continuous pores having an average pore diameter of 0.01 to 20 micrometers and a thickness of 100 micrometers or more. |