| abstract |
The invention relates to fluorometry, and in particular to methods and apparatus for time-delayed detection of fluorescence in a sample, for example for use in a clinical setting. Exemplary embodiments disclosed relate to a fluorometer ( 100 ) comprising a light source ( 101 ), a light detector ( 102 ), a sample holder ( 103 ) disposed between the light source and light detector, a motor ( 104 ); and a light transmission modulator ( 105 ) disposed around the sample holder and comprising a pair of plates ( 106, 107 ) attached to the motor for rotation about a common axis ( 108 ), the pair of plates arranged to allow transmission from the source to the sample in a first rotated position, to allow transmission from the sample to the detector in a second rotated position and to block direct light transmission between the source and detector in both first and second rotated positions. |