Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a030dfd9caa76f6a3c490626ca86bd1f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_09a6026e48efb777c87f8ded273cd923 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_747b66250748fe94a0ecb4a9aaaef903 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 |
filingDate |
2011-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9e2282edb688bbc32cefa319c9e5774 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca543e148ad19cdb0dafe57479b1c6b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f6c90001a70fbef660208d023b00c92 |
publicationDate |
2014-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2014296268-A1 |
titleOfInvention |
Therapeutic methods and compositions involving allosteric kinase inhibition |
abstract |
The present invention is directed to methods and compositions for suppressing lymphangiogenesis, angiogenesis and/or tumor growth. The methods comprise contacting the tumor with a compound that (i) stabilizes a protein kinase in the inactive state and (ii) is not an ATP competitive inhibitor of the protein kinase in the active state. |
priorityDate |
2010-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |