Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb8f3eba86915d967beefc175437273a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d66e86b5c8b8069bd3cb11b882f8ef74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_00eed9abfcfccce03614a85b5b0c1a35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6bf7b8a25cb023e97cee74487d6b72d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f1620d255aca0268ec9ed7e84fabf296 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_de3a20641832993e5ae30cb014f9d683 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33e548b3227aa17d643469c5e670bda3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d27140f0659aa6231b88dc00f6e661be |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5044 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0459 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5017 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate |
2012-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb34c04d1860aba78944d8512371578b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03cac2ece2a2380d47e0c7c5ef32277e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_168bc8d95487685356ab8b9e4ff2b715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_656eda22251d7b28e61025ef931971ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2069c70b3e99cecef79b84ba307d4b5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_266cb4f97b0f80a0fc93327123b985b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d84220f3fc6293f0ef47d43f99861590 |
publicationDate |
2014-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2014294725-A1 |
titleOfInvention |
Uses of labeled hsp90 inhibitors |
abstract |
The invention concerns various methods of using labeled HSP90 inhibitors to improve treatment of cancer patients with HSP90 inhibitors, including ex vivo and in vivo methods for determining whether a tumor will likely respond to therapy with an HSP90 inhibitor. The disclosure provides a method for determining whether a tumor will likely respond to therapy with an HSP90 inhibitor which comprises the following steps: (a) contacting the tumor or a sample containing cells from the tumor with a detectably labeled HSP90 inhibitor which binds preferentially to a tumor-specific form of HSP90; (b) measuring the amount of labeled HSP90 inhibitor bound to the tumor or the tumor cells in the sample; and (c) comparing the amount of labeled HSP90 inhibitor bound to the tumor or the tumor cells in the sample measured in step (b) to the amount of labeled-HSP90 inhibitor bound to a reference. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9701678-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11607465-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11065350-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9555137-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10793570-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10676476-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10617772-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10000494-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014242602-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10329293-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10167285-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9994573-B2 |
priorityDate |
2011-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |